Means to an End : Apoptosis and Other Cell Death Mechanisms
Means to an End : Apoptosis and Other Cell Death Mechanisms
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Author: Douglas R Green
Page Count: 220 pages
Published Date: 31 Dec 2010
Publisher: Cold Spring Harbor Laboratory Press
Publication Country: United States
Language: English
Type: PDF
ISBN: 9780879698874
File Name: Means.to.an.End.Apoptosis.and.Other.Cell.Death.Mechanisms.pdf
Download Link: Means to an End Apoptosis and Other Cell Death Mechanisms
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One million cells in our bodies die every second--they commit suicide by a mechanism known as apoptosis. Apoptosis is essential for survival of the body as a whole and has critical roles in various developmental processes and the immune system. In Means To An End, Douglas Green provides a clear and comprehensive view of apoptosis and other cell death mechanisms. Taking a bottom-up approach, he starts with the enzymes that perform the execution process (a family of proteases termed caspases) and examines their cellular targets and the ways in which they are activated. He then looks at the molecular machinery that links signals that cause cell death to caspases, emphasizing the importance of the BCL-2 family of proteins and the role of cytochrome c released from mitochondria. The final stage of the process, phagocytic removal of dead or dying cells, is also covered. Green outlines the roles of apoptosis and death mechanisms such as necrosis in embryogenesis, neuronal selection, and the development of self-tolerance in the immune system. In addition, he explains how cell death defends the body against cancer and traces the evolutionary origins of the apoptosis machinery back over a billion years. The book is thus of great use to all biologists interested in how cells function in the context of multicellular organisms and will appeal to everyone from undergraduates encountering the topic for the first time to researchers actively working in the field.
Read online Means to an End : Apoptosis and Other Cell Death Mechanisms Buy Means to an End : Apoptosis and Other Cell Death Mechanisms Download Means to an End : Apoptosis and Other Cell Death Mechanisms for pc, mac, kindle, readers Download to iPad/iPhone/iOS, B&N nook Means to an End : Apoptosis and Other Cell Death Mechanisms
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Means to an End : Apoptosis and Other Cell Death Mechanisms by Douglas R Green
Author: Douglas R Green
Page Count: 220 pages
Published Date: 31 Dec 2010
Publisher: Cold Spring Harbor Laboratory Press
Publication Country: United States
Language: English
Type: PDF
ISBN: 9780879698874
File Name: Means.to.an.End.Apoptosis.and.Other.Cell.Death.Mechanisms.pdf
Download Link: Means to an End Apoptosis and Other Cell Death Mechanisms
---------------------------------------------------------------
One million cells in our bodies die every second--they commit suicide by a mechanism known as apoptosis. Apoptosis is essential for survival of the body as a whole and has critical roles in various developmental processes and the immune system. In Means To An End, Douglas Green provides a clear and comprehensive view of apoptosis and other cell death mechanisms. Taking a bottom-up approach, he starts with the enzymes that perform the execution process (a family of proteases termed caspases) and examines their cellular targets and the ways in which they are activated. He then looks at the molecular machinery that links signals that cause cell death to caspases, emphasizing the importance of the BCL-2 family of proteins and the role of cytochrome c released from mitochondria. The final stage of the process, phagocytic removal of dead or dying cells, is also covered. Green outlines the roles of apoptosis and death mechanisms such as necrosis in embryogenesis, neuronal selection, and the development of self-tolerance in the immune system. In addition, he explains how cell death defends the body against cancer and traces the evolutionary origins of the apoptosis machinery back over a billion years. The book is thus of great use to all biologists interested in how cells function in the context of multicellular organisms and will appeal to everyone from undergraduates encountering the topic for the first time to researchers actively working in the field.
Read online Means to an End : Apoptosis and Other Cell Death Mechanisms Buy Means to an End : Apoptosis and Other Cell Death Mechanisms Download Means to an End : Apoptosis and Other Cell Death Mechanisms for pc, mac, kindle, readers Download to iPad/iPhone/iOS, B&N nook Means to an End : Apoptosis and Other Cell Death Mechanisms
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